One member of a pair or series of genes that occupy a specific position on a specific chromosome. MPN community discusses "allele burden" as a metric that may or may not be related t [..]

When the number of red blood cells is below normal, it can result in fatigue, weakness, and shortness of breath.

The process of programmed cell death (PCD) that may occur in multicellular organisms.

 Enzymes essential to cell proliferation. The enzyme helps the dividing cell dispense its genetic materials to its daughter cells

Undeveloped, immature blood cells in the bone marrow that develop into mature blood cells

A procedure used to remove soft tissue, called marrow, from inside the bone. A reading of a Bone Marrow Biopsy to detect the amount of fibrosis in the bone marrow is often used in part to diagnose mye [..]

Any of various cytokines produced in acute and chronic inflammation that mobilize and activate white blood cells.

In the pharmaceutical industry, a compendium is a comprehensive listing of drugs. It typically includes a summary of the pharmacologic characteristics of each listed drug or biological; information on [..]

A blood test used to evaluate your overall health and detect a wide range of disorders. Used in diagnosing someone with PV, ET and MF among other conditions. A complete blood count test measures sever [..]

A type of protein that has an effect on the immune system. Some cytokines stimulate the immune system and others slow it down. Cytokines are often produced by immune cells but can also be produced by [..]